Oxidative Stress in Vitiligo: Catalase Defects, H2O2 Burden, and Redox-Immune Crosstalk
Key Takeaways Lesional skin shows elevated H2O2 with reduced antioxidant enzyme activity, notably catalase and glutathione peroxidase. Redox stress perturbs […]
melanogenesis
Genetics of Vitiligo: GWAS Loci Across Immune and Melanocyte Pathways
Key Takeaways Vitiligo is a complex, polygenic disorder with loci mapping to immune regulation (e.g., HLA, NLRP1, PTPN22, IL2RA) and