St. John’s Wort for Vitiligo: A Simple, Low-Cost Way to Partially Ease the Problem
St. John’s wort has long been used in phytomedicine as a natural antidepressant, antispasmodic, and diuretic—and also as a photosensitizer. […]
St. John’s wort has long been used in phytomedicine as a natural antidepressant, antispasmodic, and diuretic—and also as a photosensitizer. […]
Microcurrent Therapy for Vitiligo: A Scientific Review of Innovative Methods Vitiligo is a challenge medicine has been tackling for decades.
Key Takeaways Face/neck respond fastest: perifollicular islands in 4–8 weeks, meaningful F-VASI drops by 8–12 weeks—best as nightly monotherapy or
Key Takeaways Face/neck respond best to tacrolimus 0.1%, with earlier perifollicular islands and higher chances of achieving F-VASI50/75 when combined
Key Takeaways First-line on face/neck: calcineurin inhibitors (tacrolimus 0.1% or pimecrolimus 1%) as steroid-sparing agents. Backbone for generalized disease: NB-UVB
Key Takeaways Highest efficacy on face/neck with early perifollicular islands; moderate on trunk/limbs; limited on acral sites without phototherapy add-ons.
Key Takeaways Targeted therapy ideal for focal lesions, active edges, and facial/neck sites; enables high local dose while sparing uninvolved
Key Takeaways Backbone therapy for generalized/nonsegmental vitiligo; best outcomes on face/neck, slower on acral sites. Typical schedule 2–3×/week for 24–48
Key Takeaways Topical and oral tofacitinib show signals of repigmentation in case series/open studies, with best facial responses. NB-UVB appears