Tacrolimus 0.1% in Vitiligo: Efficacy by Anatomic Zone (Face/Neck vs Trunk vs Acral)
Key Takeaways Highest efficacy on face/neck with early perifollicular islands; moderate on trunk/limbs; limited on acral sites without phototherapy add-ons. […]
Key Takeaways Highest efficacy on face/neck with early perifollicular islands; moderate on trunk/limbs; limited on acral sites without phototherapy add-ons. […]
Key Takeaways First-line option on trunk/limbs; avoid continuous high-potency use on face, folds, genital skin—prefer calcineurin inhibitors there. Intermittent schedules
Key Takeaways Pimecrolimus 1% cream showed superiority to vehicle on facial endpoints (F-VASI) over ~12–24 weeks in split-face and parallel-arm
Key Takeaways Face/neck consistently show the best repigmentation with tacrolimus 0.1%; early perifollicular islands predict response. Acral (hands/feet) and longstanding